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Job Post Details
Senior Research Associate, Organic & Medicinal Chemistry - job post
Locatie
Volledige vacaturetekst
At Genmab, we’re committed to building extra[not]ordinary futures together, by developing antibody products and pioneering, knock-your-socks-off therapies that change the lives of patients and the future of cancer treatment and serious diseases. From our people who are caring, candid, and impact-driven to our business, which is innovative and rooted in science, we believe that being proudly unique, determined to be our best, and authentic is essential to fulfilling our purpose.
The Role
We are seeking a highly motivated and skilled Senior Research Associate Organic and Medicinal Chemistry, to join our dynamic team in the Discovery Department at Genmab. As a key member of our new chemical lab, you will play an essential role in supporting the development of Antibody Drug Conjugates (ADCs) in a fast-paced and innovative biotech environment. Your hands-on expertise in organic and medicinal chemistry will be crucial in executing experiments, synthesizing compounds, and optimizing processes to advance our research and development projects.
If you are a driven and experienced technician looking to make a significant impact in a cutting-edge biotech environment, we invite you to apply for this exciting opportunity.
Responsibilities
Optimization and Analysis: Conduct structure-activity relationship (SAR) studies and support the optimization of lead compounds. Utilize advanced analytical techniques, including HPLC, LC-MS, and NMR, to characterize and purify compounds.
Laboratory Operations: Perform hands-on laboratory work, including the execution of experiments and maintenance of lab equipment. Ensure high-quality data collection and adhere to laboratory protocols and best practices.
Compound Design and Synthesis: Assist in the development and synthesis of novel linkers and payloads to support ADC discovery and development projects. Apply medicinal chemistry principles to assist in designing compounds with optimal pharmacological properties and ensuring effective conjugation to Genmab’s antibody formats.
Collaboration: Work closely with chemists and cross-functional teams, including biologists and pharmacologists, to support research projects and achieve project milestones. Contribute to the planning and execution of experiments and provide technical support as needed.
Innovation and Improvement: Stay informed about the latest advancements in organic synthesis and medicinal chemistry. Apply innovative approaches to problem-solving and contribute to the improvement of laboratory techniques and procedures.
Documentation and Reporting: Maintain accurate and detailed records of experimental procedures, results, and analyses. Assist in the preparation of scientific reports and documentation for internal use.
Quality and Compliance: Ensure all work is conducted in compliance with company policies, industry regulations, and safety standards. Participate in safety and compliance training as required.
Requirements
Educational Background: Master’s degree in Organic Chemistry, Analytical Chemistry, Medicinal Chemistry, or a related field. Relevant certifications or additional training in laboratory techniques are a plus.
Experience: > 3 years of hands-on experience in organic and medicinal chemistry within a laboratory setting. Proven ability to conduct experiments, synthesize compounds, and analyze data effectively.
Technical Skills: Proficiency in organic synthesis techniques and analytical methods, including NMR, MS, and HPLC. Experience with high-throughput screening and SAR analysis is desirable.
Analytical Thinking: Strong problem-solving skills with the ability to analyze complex data and derive actionable insights. Demonstrated ability to execute experiments independently and effectively.
Collaboration: Excellent interpersonal and communication skills, with a demonstrated ability to work effectively in a team-oriented environment. Experience working with cross-functional teams is highly desirable.
Adaptability: Ability to thrive in a fast-paced biotech environment with a proactive and flexible approach to work. Willingness to take on diverse tasks and responsibilities as needed.
Passion for Innovation: Enthusiasm for working in an innovative biotech setting and a commitment to supporting scientific research and development.
About You
- You are passionate about our purpose and genuinely care about our mission to transform the lives of patients through innovative cancer treatment
- You bring rigor and excellence to all that you do. You are a fierce believer in our rooted-in-science approach to problem-solving
- You are a generous collaborator who can work in teams with diverse backgrounds
- You are determined to do and be your best and take pride in enabling the best work of others on the team
- You are not afraid to grapple with the unknown and be innovative
- You have experience working in a fast-growing, dynamic company (or a strong desire to)
- You work hard and are not afraid to have a little fun while you do so
Locations
Genmab leverages the effectiveness of an agile working environment, when possible, for the betterment of employee work-life balance. Our offices are designed as open, community-based spaces that work to connect employees while being immersed in our state-of-the-art laboratories. Whether you’re in one of our collaboratively designed office spaces or working remotely, we thrive on connecting with each other to innovate.
About Genmab
Genmab is an international biotechnology company with a core purpose guiding its unstoppable team to strive towards improving the lives of patients through innovative and differentiated antibody therapeutics. For more than 20 years, its passionate, innovative and collaborative team has invented next-generation antibody technology platforms and leveraged translational research and data sciences, which has resulted in a proprietary pipeline including bispecific T-cell engagers, next-generation immune checkpoint modulators, effector function enhanced antibodies and antibody-drug conjugates. To help develop and deliver novel antibody therapies to patients, Genmab has formed 20+ strategic partnerships with biotechnology and pharmaceutical companies. By 2030, Genmab’s vision is to transform the lives of people with cancer and other serious diseases with Knock-Your-Socks-Off (KYSO™) antibody medicines.
Established in 1999, Genmab is headquartered in Copenhagen, Denmark with locations in Utrecht, the Netherlands, Princeton, New Jersey, U.S. and Tokyo, Japan.
Our commitment to diversity, equity, and inclusion
We are committed to fostering workplace diversity at all levels of the company and we believe it is essential for our continued success. No applicant shall be discriminated against or treated unfairly because of their race, color, religion, sex (including pregnancy, gender identity, and sexual orientation), national origin, age, disability, or genetic information. Learn more about our commitments on our website.
Genmab is committed to protecting your personal data and privacy. Please see our privacy policy for handling your data in connection with your application on our website Job Applicant Privacy Notice (genmab.com).
Please note that if you are applying for a position in the Netherlands, Genmab’s policy for all permanently budgeted hires in NL is initially to offer a fixed-term employment contract for a year, if the employee performs well and if the business conditions do not change, renewal for an indefinite term may be considered after the fixed-term employment contract.